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Scanning Probe Microscopy

Scanning Probe Microscopy
"Seeing is Believing"

We employ scanning ion conductance microscopy (SICM) and atomic force microscopy (AFM) to noninvasively scan the surface of biological membrane mimics and live cells to investigate biological interactions at the membrane interface under physiologically relevant conditions with nanometer resolution. These imaging capabilities are unmet by other analytical techniques available today.

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Chin HK, Gillissen JJ, Miyako E, Cho NJ

"Microfluidic Liquid Cell Chamber for Scanning Probe Microscopy Measurement Application." 

Review of Scientific Instruments 2019; 90(4), 46105.


Kim SO, Jackman JA, Mochiduki M, Yoon BK, Hayashi T, Cho NJ

"Correlating Single-Molecule and Ensemble-Average Measurements of Peptide Adsorption onto Different Inorganic Materials." 

Physical Chemistry Chemistry Physics 2016; 18(21), 14454-14459.


Kim JH, Choi MH, Jung GE, Ferhan AR, Cho NJ, Cho SJ

"Dimensional Comparison between Amplitude-Modulation Atomic Force Microscopy and Scanning Ion Conductance Microscopy of Biological Samples." 

Japanese Journal of Applied Physics 2016; 55(8S1), 08NB18.


Lee JS, Song JK, Kim SO, Kim SB, Lee WJ, Jackman JA, Kim DC, Cho NJ*, Lee JC*


(* denotes equal corresponding authors)

"Multifunctional Hydrogel Nano-Probes for Atomic Force Microscopy." 

Nature Communications 2016; 7, 11566.


Mochiduki M, Oguchi M, Kim SO, Jackman JA, Ogawa T, Lkhamsuren G, Cho NJ*, Hayashi T*


(* denotes equal corresponding authors)

"Quantitative Evaluation of Peptide-Material Interactions by a Force Mapping Method: Guidelines for Surface Modification." 

Langmuir 2015; 31(29), 8006-8012. 


Noh HA, Jung GE, Kim S, Yun SH, Jo A, Kahng SJ, Cho NJ*, Cho SJ*


Cover Illustration

(* denotes equal corresponding authors)

"Multi-Point Force Feedback Leveling of Massively Parallel Tip Arrays in Scanning Probe Lithography." 

Small 2015; 11(35), 4526-4531. 


Jung GE, Noh HA, Shin YK, Kahng SJ, Baik KY, Kim HB, Cho NJ*, Cho SJ*


Cover Illustration

(* denotes equal corresponding authors)

"Closed-Loop ARS Mode for Scanning Ion Conductance Microscopy with Improved Speed and Stability for Live Cell Imaging Applications." 

Nanoscale 2015; 7(25), 10989-10997.


Kim JH, Kim SO, Cho NJ


"Alternative Configuration Scheme for Signal Amplification with Scanning Ion Conductance Microscopy." 

Review of Scientific Instruments 2015; 86, 023706.


Anariba F, Ahn JH, Jung GE, Cho NJ, Cho SJ

"Biophysical Applications of Scanning Ion Conductance Microscopy (SICM)." 

Modern Physics Letters B 2012; 26(5), 1130003.

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