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Infectious Diseases - Antimicrobial

Infectious Diseases-Antibacterial

With the growing challenges of drug-resistant bacteria and the need for new classes of antibiotics,  we are developing various classes of nanostructured antibacterial agents for healthcare and biotechnology applications. Using our engineering strategies, we explore their potential as next-generation antibacterial solutions while gaining mechanistic insights.

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Jackman JA*, Yoon BK*, Mokrzecka N, Kohli GS, Valle-González ER, Zhu X, Pumera M, Rice SA, Cho NJ

(* denotes equal first authors)

"Graphene Oxide Mimics Biological Signaling Cue to Rescue Starving Bacteria." 

Advanced Functional Materials 2021, 2102328.


Sut TN*, Valle-González ER*, Yoon BK*, Park S, Jackman JA**, Cho NJ**

(* denotes equal first authors, ** denotes equal corresponding authors)

"Engineered Lipid Bicelle Nanostructures for Membrane-Disruptive Antibacterial Applications.

Applied Materials Today 2021, 22: 100947.


Yoon BK, Park H, Zhdanov VP, Jackman JA*, Cho NJ*


(* denotes equal corresponding authors)

"Real-Time Nanoplasmonic Sensing of Three-Dimensional Morphological Changes
in a Supported Lipid Bilayer and Antimicrobial Testing Applications.

Biosensors and Bioelectronics 2020; 112768.


Yoon BK, Park S, Ma GJ, Kolahdouzan K, Zhdanov VP, Jackman JA*, Cho NJ*


(* denotes equal corresponding authors)

"Competing Interactions of Fatty Acids and Monoglycerides Trigger Synergistic Phospholipid Membrane Remodeling." 

The Journal of Physical Chemistry Letters 2020; 11, 4951-4957.


Valle-González ER, Jackman JA, Yoon BK, Mokrzeka N, Cho NJ

"pH-Dependent Antibacterial Activity of Glycolic Acid: Implications for Anti-Acne Formulations." 

Scientific Reports 2020; 10, 7491.


Yoon BK, Park S, Jackman JA*, Cho NJ*


(* denotes equal corresponding authors)

"Supported Lipid Bilayer Platform for Characterizing the Optimization of Mixed Monoglyceride Nano-Micelles." 

Applied Materials Today 2020; 19, 100598.


Yoon BK, Jackman JA, Park S, Mokrzecka N, Cho NJ

"Characterizing the Membrane-Disruptive Behavior of Dodecylglycerol Using Supported Lipid Bilayers." 

Langmuir 2019; 35(9) 3568-3575.


Valle-González ER, Jackman JA, Yoon BK, Park S, Sut TN, Cho NJ

"Characterizing How Acidic pH Conditions Affect the Membrane-Disruptive Activities of Lauric Acid and Glycerol Monolaurate." 

Langmuir 2018; 34(45), 13745-13753.


Yoon BK, Jackman JA, Valle-González ER, Cho NJ

"Antibacterial Free Fatty Acids and Monoglycerides: Biological Activities, Experimental Testing, and Therapeutic Applications." 

International Journal of Molecular Sciences 2018; 19(4), 1114.

Special Issue on "Molecular Signaling and Nanobiotechnology: Prospects for Future Antimicrobial Therapy".


Chilambi GS, Gao I, Yoon BK, Park S, Kawakami L, Ravikumar V, Chan-Park M, Cho NJ, Bazan G, Kline K, Rice S, Hinks J

"Membrane Adaptation Limitations in Enterococcus faecalis Underlie Sensitivity and the Inability to Develop Significant Resistance to Conjugated Oligoelectrolytes." 

RSC Advances 2018; 8(19), 10284-10293. 


Kawakami LM*, Yoon BK*, Jackman JA, Knoll W, Weiss PS, Cho NJ


(* denotes equal first authors)

"Understanding How Sterols Regulate Membrane Remodeling in Supported Lipid Bilayers." 

Langmuir 2017; 33(51) 14756-14765.


Yoon BK, Jackman JA, Kim MC, Sut TN, Cho NJ

"Correlating Membrane Morphological Responses with Micellar Aggregation Behavior of Capric Acid and Monocaprin." 

Langmuir 2017; 33(11), 2750 - 2759.


Brown MA*, Potroz MG*, Teh SW, Cho NJ


(* denotes equal first authors)

"Natural Products for the Treatment of Chlamydiaceae Infections." 

Microorganisms 2016; 4(4), 39.

Special Issue on "Chlamydia-like Bacteria: Evolution, Pathogenicity, Diagnostics and Treatment". 


Jackman JA, Yoon BK, Li D, Cho NJ

"Nanotechnology Formulations for Antibacterial Free Fatty Acids and Monoglycerides." 

Molecules 2016; 21(3), 305. 

Invited Special Issue on "Antibiotics & Superbugs: New Strategies to Combat Antimicrobial Resistance".


Yoon BK, Jackman JA, Kim MC, Cho NJ


"Spectrum of Membrane Morphological Responses to Antibacterial Fatty Acids and Related Surfactants." 

Langmuir 2015; 31(37), 10223-10232.


Potroz MG, Cho NJ

"Natural Products for the Treatment of Trachoma and Chlamydia Trachomatis." 

Molecules 2015; 20(3), 4180-4203. 

Invited Special Issue on "Natural Products as Leads or Drugs against Neglected Tropical Diseases".

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